Relationship between diet, inflammation and cancer: Key factor found

A category of lipids known as sphingolipids may be an important link in the relationship between diet, inflammation and cancer, a team of scientists has found. They have provided evidence that a sphingolipid metabolite called sphingosine-1-phosphate (S1P) found in both mammalian food products and generated by normal human cells can contribute to inflammation of the colon, inflammatory bowel disease (IBD) and inflammation-associated colon cancer, whereas soy and plant-type sphingolipids called sphingadienes may protect against these conditions.



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